ZBED5

Across TCGA patient cohorts, ZBED5 mutation is significantly associated with the RNA expression of many other genes, with 2,073 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED5-associated genes across cancer lineages are LINC00566, COX5A, and KLHDC7A. Each is linked with ZBED5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED5-to-partner and partner-to-ZBED5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00566 grouped by ZBED5-low versus ZBED5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED5→partner) and Y-score (partner→ZBED5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC00566 →	+0.083	+5.192	.006	.001	3	1
UCEC	COX5A →	+0.361	+2.513	.001	<.001	3	1
UCEC	KLHDC7A →	+0.822	+1.925	<.001	.004	3	1
UCEC	GIMAP7 →	+0.651	+1.777	.001	.002	3	1
UCEC	GATA2 →	-0.989	-2.890	<.001	.001	3	1
UCEC	C14orf28 →	+0.263	+2.147	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,073 associations by consensus.

LINC00566 by ZBED5 expression — BRCA

Explore this box plot interactively →