ZBED4

Across TCGA patient cohorts, ZBED4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,630 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZBED4-associated genes across cancer lineages are PDGFRB, SH3RF2, and LINC01399. Each is linked with ZBED4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED4-to-partner and partner-to-ZBED4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBED4 versus PDGFRB in BRCA, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED4→partner) and Y-score (partner→ZBED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDGFRB →	-0.969	-0.669	.005	.006	3	2
LSCC	SH3RF2 →	-1.244	-0.550	.006	<.001	3	2
LSCC	LINC01399 →	+1.703	+0.529	<.001	.001	3	2
LUAD	UBA52P3 →	+0.358	+0.621	<.001	<.001	3	2
UCEC	GLIS3 →	-1.066	-0.649	.003	.002	3	2
LUAD	AMMECR1L →	+0.502	+0.563	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,630 associations by consensus.

ZBED4 vs PDGFRB — BRCA

Explore this scatter interactively →