ZBBX

Across TCGA cell cohorts, ZBBX RNA expression is significantly associated with the go_rna of many other GO terms, with 1,474 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBBX-associated GO terms across cancer lineages are Transport along microtubule, Cytoplasmic translation, and Protein localization to ciliary transition zone. Each is linked with ZBBX in more than 6 cancer types. Because this analysis shows association rather than direction, both ZBBX-to-partner and partner-to-ZBBX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by ZBBX-low versus ZBBX-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBBX→partner) and Y-score (partner→ZBBX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Transport along microtubule →	+0.065	+0.816	<.001	.003	3	7
BREAST	Cytoplasmic translation →	+0.059	+0.138	.005	.006	3	7
BREAST	Protein localization to ciliary transition zone →	+0.059	+0.200	.004	.006	3	7
LUNG_SCLC	Microtubule-based transport →	+0.058	+0.639	.002	.009	3	7
CNS	COP9 signalosome assembly →	+0.108	+0.368	<.001	.004	3	6
BREAST	Cilium or flagellum-dependent cell motility →	-0.054	-0.157	<.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,474 associations by consensus.

Transport along microtubule by ZBBX expression — LUNG_SCLC

Explore this box plot interactively →