YY1AP1

Across TCGA patient cohorts, YY1AP1 mutation is significantly associated with the RNA expression of many other genes, with 4,242 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YY1AP1-associated genes across cancer lineages are LACTB, NDUFA9, and NTAN1. Each is linked with YY1AP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both YY1AP1-to-partner and partner-to-YY1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LACTB grouped by YY1AP1-low versus YY1AP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YY1AP1→partner) and Y-score (partner→YY1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LACTB →	+0.649	+3.584	.001	.002	3	3
SKCM	NDUFA9 →	+0.275	+2.632	.007	.005	3	3
UCEC	NTAN1 →	+0.565	+3.119	<.001	<.001	3	3
UCEC	ITGAE →	+0.523	+3.115	<.001	<.001	3	3
UCEC	MRPL49 →	+0.526	+3.000	<.001	<.001	3	3
UCEC	BUB3 →	+0.533	+2.643	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

LACTB by YY1AP1 expression — SKCM

Explore this box plot interactively →