YY1AP1

Across TCGA cell cohorts, YY1AP1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible YY1AP1-associated genes across cancer lineages are AVP, ZAN, and FTMT. Each is linked with YY1AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YY1AP1-to-partner and partner-to-YY1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by YY1AP1-low versus YY1AP1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YY1AP1→partner) and Y-score (partner→YY1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	AVP →	+0.097	+4.977	<.001	.002	3	1
SOFT_TISSUE	ZAN →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
BLOOD_Leukemia	GUCA2A →	+0.052	+5.969	<.001	.001	3	1
BLOOD_Leukemia	MT1HL1 →	+0.419	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR1D4 →	+0.069	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

AVP by YY1AP1 expression — SOFT_TISSUE

Explore this box plot interactively →