YWHAQP5

Across TCGA pan-cancer cohorts, YWHAQP5 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of YWHAQP5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where YWHAQP5 RNA is repressed in tumor relative to normal tissue. In most cancer types YWHAQP5 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and STAD are the cancer types where YWHAQP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YWHAQP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.051	<.001	8	view →
KIRP	All	II,III,IV	−0.081	.009	6	view →
STAD	All	All	+0.241	.002	3	view →
LIHC	All	II,III,IV	+0.018	.008	2	view →
BLCA	Female	IV	+0.070	.010	1	view →
KICH	All	All	−0.046	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

YWHAQP5–KIRC

Open the KIRC breakdown →