Q-omics provides the consensus-scored YWHAQP5 profile across patient tissues and cancer cell-line models. YWHAQP5 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, YWHAQP5 is differentially expressed in 6, with the highest sampling consensus in KIRC. Additionally, YWHAQP5 RNA expression shows 12,303 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight LUAD, KIRC, and LSCC as cancer lineages where YWHAQP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for YWHAQP5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes YWHAQP5 survival associations across molecular data types. YWHAQP5 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible YWHAQP5 RNA expression–survival associations across cancer types. High YWHAQP5 expression shows unfavorable associations in KIRC, LIHC, MESO and CHOL, but favorable associations in LUAD and UCS. The LUAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LUAD as the clearest survival context for YWHAQP5 RNA expression.
This table summarizes YWHAQP5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for YWHAQP5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. YWHAQP5 shows lower tumor expression in KIRC, KIRP and KICH and higher tumor expression in STAD, LIHC and BLCA. The KIRC box plot shows higher YWHAQP5 RNA expression in normal versus tumor tissue (log2 FC = −0.051, t-test p < 0.001).
This table shows molecular features associated with YWHAQP5 in patient tissues and cancer cell lines. In patient samples, YWHAQP5 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
