YWHAEP7

Across TCGA patient cohorts, YWHAEP7 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YWHAEP7-associated genes across cancer lineages are RNY1P1, MIR199B, and RNU6-440P. Each is linked with YWHAEP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both YWHAEP7-to-partner and partner-to-YWHAEP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY1P1 grouped by YWHAEP7-low versus YWHAEP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAEP7→partner) and Y-score (partner→YWHAEP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNY1P1 →	+0.464	+4.750	<.001	.005	3	1
UCEC	MIR199B →	+0.337	+4.267	<.001	.009	3	1
UCEC	RNU6-440P →	+0.373	+5.464	<.001	.001	3	1
UCEC	RNU6-466P →	+0.500	+3.661	.004	.009	3	1
UCEC	LINC00363 →	+0.298	+4.442	<.001	.007	3	1
UCEC	TTTY15 →	+0.015	+4.430	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RNY1P1 by YWHAEP7 expression — UCEC

Explore this box plot interactively →