YWHAB

Across TCGA patient cohorts, YWHAB protein abundance is significantly associated with the RNA expression of many other genes, with 12,663 significant associations in total. COAD shows the largest number of these associations.

The most reproducible YWHAB-associated genes across cancer lineages are SERINC3, ELMO2, and BLCAP. Each is linked with YWHAB in more than 5 cancer types. Because this analysis shows association rather than direction, both YWHAB-to-partner and partner-to-YWHAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YWHAB versus SERINC3 in COAD, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAB→partner) and Y-score (partner→YWHAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SERINC3 →	+0.524	+0.392	<.001	<.001	3	6
COAD	ELMO2 →	+0.674	+0.333	.002	.002	3	6
BRCA	BLCAP →	+0.538	+0.240	<.001	<.001	3	6
COAD	OSER1 →	+0.666	+0.365	<.001	<.001	3	5
LUAD	SYS1 →	+0.513	+0.261	<.001	<.001	3	5
BRCA	ITCH →	+0.439	+0.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,663 associations by consensus.

YWHAB vs SERINC3 — COAD

Explore this scatter interactively →