YWHAB

Across TCGA cell cohorts, YWHAB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,193 significant associations in total. BONE shows the largest number of these associations.

The most reproducible YWHAB-associated GO terms across cancer lineages are Mitotic centrosome separation, IRE1-mediated unfolded protein response, and Protein import into peroxisome membrane. Each is linked with YWHAB in more than 12 cancer types. Because this analysis shows association rather than direction, both YWHAB-to-partner and partner-to-YWHAB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by YWHAB-low versus YWHAB-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAB→partner) and Y-score (partner→YWHAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Mitotic centrosome separation →	+0.154	+0.837	<.001	<.001	3	13
STOMACH	IRE1-mediated unfolded protein response →	+0.159	+0.763	<.001	<.001	3	13
BONE	Protein import into peroxisome membrane →	+0.134	+0.500	<.001	.001	3	12
STOMACH	Endosomal transport →	+0.075	+0.797	.001	.002	3	11
BONE	Protein linear deubiquitination →	+0.885	+0.488	.002	.004	3	11
BLOOD_Leukemia	Protein autoubiquitination →	+0.027	+0.438	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,193 associations by consensus.

Mitotic centrosome separation by YWHAB expression — CNS

Explore this box plot interactively →