YTHDF3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, YTHDF3 mutation is significantly associated with the RNA expression of many other genes, with 4,678 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YTHDF3-associated genes across cancer lineages are MIR4510, RN7SL248P, and BAG3. Each is linked with YTHDF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YTHDF3-to-partner and partner-to-YTHDF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDF3→partner) and Y-score (partner→YTHDF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMIR4510 →+0.236+4.757<.001.00432
UCECRN7SL248P →+0.052+2.815<.001.00232
UCECBAG3 →+0.608+1.947<.001<.00132
UCECEME1 →+0.646+4.212<.001<.00132
UCECABHD3 →+0.716+2.233<.001<.00132
UCECMIS18A →+0.567+2.536<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,678 associations by consensus.

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