YPEL4

Across TCGA patient cohorts, YPEL4 protein abundance is significantly associated with the RNA expression of many other genes, with 168 significant associations in total. GBM shows the largest number of these associations.

The most reproducible YPEL4-associated genes across cancer lineages are HHATL, SEC14L5, and PDAP1. Each is linked with YPEL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both YPEL4-to-partner and partner-to-YPEL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YPEL4 versus HHATL in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL4→partner) and Y-score (partner→YPEL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HHATL →	+1.642	+0.534	.002	.002	3	1
GBM	SEC14L5 →	+1.901	+0.500	.005	<.001	3	1
GBM	PDAP1 →	-0.297	-0.429	.006	.006	3	1
GBM	P3H3 →	-0.643	-0.497	<.001	<.001	3	1
GBM	ENO2 →	-0.706	-0.493	.002	.002	3	1
GBM	TSPO2 →	+0.635	+0.558	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 168 associations by consensus.

YPEL4 vs HHATL — GBM

Explore this scatter interactively →