YPEL4

Across TCGA cell cohorts, YPEL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,961 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible YPEL4-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with YPEL4 in more than 15 cancer types. Because this analysis shows association rather than direction, both YPEL4-to-partner and partner-to-YPEL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by YPEL4-low versus YPEL4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL4→partner) and Y-score (partner→YPEL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.199	+1.003	<.001	.001	3	16
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.195	+1.003	<.001	.001	3	15
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.170	+0.997	<.001	.001	3	14
OESOPHAGUS	Regulation of myoblast fusion →	+0.179	+1.003	<.001	.001	3	14
OESOPHAGUS	Regulation of macroautophagy →	+0.093	+0.817	<.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of signal transduction by p53 class mediator →	+0.082	+0.388	.003	.007	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,961 associations by consensus.

Negative regulation of myoblast fusion by YPEL4 expression — OESOPHAGUS

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