YPEL3

Across TCGA patient cohorts, YPEL3 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,685 significant associations in total. OV shows the largest number of these associations.

The most reproducible YPEL3-associated proteins across cancer lineages are MDH2, MRPL12, and AHNAK_S177. Each is linked with YPEL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YPEL3-to-partner and partner-to-YPEL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YPEL3 versus MDH2 in BRCA, with a Pearson correlation of 0.92.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL3→partner) and Y-score (partner→YPEL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MDH2 →	+1.618	+0.945	<.001	<.001	3	1
BRCA	MRPL12 →	+1.223	+0.945	<.001	<.001	3	1
BRCA	AHNAK_S177 →	+1.919	+0.945	.005	<.001	3	1
BRCA	AHNAK_S5077 →	+1.885	+0.911	.004	<.001	3	1
BRCA	FAM126A_T517 →	+0.931	+0.938	.009	<.001	3	1
BRCA	NKTR_S575 →	-1.106	-0.813	.003	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,685 associations by consensus.

YPEL3 vs MDH2 — BRCA

Explore this scatter interactively →