YPEL3

Across TCGA patient cohorts, YPEL3 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YPEL3-associated genes across cancer lineages are RN7SL134P, TUBBP11, and SNORD116-23. Each is linked with YPEL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YPEL3-to-partner and partner-to-YPEL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by YPEL3-low versus YPEL3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL3→partner) and Y-score (partner→YPEL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.147	+2.792	.002	.006	3	2
SKCM	TUBBP11 →	+0.136	+4.564	.005	.001	3	2
UCEC	SNORD116-23 →	+0.578	+2.654	.005	.002	3	2
SKCM	MIR549A →	+0.234	+4.385	<.001	.008	3	2
UCEC	MIR4744 →	+0.441	+2.600	.003	.005	3	1
UCEC	MIR4659A →	+0.432	+2.611	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

RN7SL134P by YPEL3 expression — UCEC

Explore this box plot interactively →