YME1L1

Across TCGA patient cohorts, YME1L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,984 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YME1L1-associated proteins across cancer lineages are CUL2, RNF40, and NCKAP1. Each is linked with YME1L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both YME1L1-to-partner and partner-to-YME1L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YME1L1 versus CUL2 in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YME1L1→partner) and Y-score (partner→YME1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CUL2 →	+0.272	+0.344	<.001	<.001	3	8
UCEC	RNF40 →	+0.215	+0.495	<.001	.001	3	6
LSCC	NCKAP1 →	+0.236	+0.306	<.001	<.001	3	5
PDAC	PFKP →	+0.495	+0.378	<.001	<.001	3	5
GBM	ABI1 →	+0.249	+0.256	<.001	<.001	3	5
BRCA	LARP4B →	+0.298	+0.350	.004	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,984 associations by consensus.

YME1L1 vs CUL2 — GBM

Explore this scatter interactively →