YLPM1

Across TCGA pan-cancer cohorts, YLPM1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated YLPM1 data layer compared with 22 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher YLPM1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated YLPM1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

HNSC, CCRCC, and LSCC are the cancer types where YLPM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	IV	0.728	1.000	.005	30	view →
CCRCC	DFS	Quartile	III,IV	0.829	0.350	.017	16	view →
LSCC	OS	Quartile	II,III,IV	0.927	0.527	.010	9	view →
COAD	DFS	Median	III,IV	1.000	0.894	.036	6	view →
PDAC	OS	Tertile	IV	0.956	0.252	.024	6	view →
LUAD	OS	Quartile	III,IV	0.993	0.651	.040	3	view →
GBM	OS	Quartile	All	0.595	0.292	.007	3	view →
UCEC	DFS	Median	All	1.000	0.937	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

YLPM1–HNSC (OS)

Open the HNSC breakdown →