YLPM1

Across TCGA pan-cancer cohorts, YLPM1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of YLPM1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where YLPM1 RNA is repressed in tumor relative to normal tissue. In most cancer types YLPM1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, HNSC, and LIHC are the cancer types where YLPM1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YLPM1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.614	<.001	9	view →
HNSC	All	All	+0.569	<.001	9	view →
LIHC	Female	II,III,IV	+0.754	<.001	8	view →
KIRC	Male	II,III,IV	−0.554	<.001	8	view →
CHOL	Male	All	+1.896	<.001	5	view →
STAD	Male	II,III,IV	+0.722	.012	4	view →
LUSC	All	All	+0.283	.005	4	view →
BRCA	Female	All	−0.217	.002	4	view →
ESCA	Female	All	+0.666	.029	2	view →
READ	All	III,IV	+0.650	.026	2	view →
KIRP	Male	All	−0.401	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

YLPM1–THCA

Open the THCA breakdown →