YLPM1

Across TCGA cell cohorts, YLPM1 mutation is significantly associated with the RNA expression of many other genes, with 868 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YLPM1-associated genes across cancer lineages are TAS2R9, RXFP3, and OOSP2. Each is linked with YLPM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YLPM1-to-partner and partner-to-YLPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R9 grouped by YLPM1-low versus YLPM1-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YLPM1→partner) and Y-score (partner→YLPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TAS2R9 →	+0.038	+4.870	<.001	.001	3	2
CNS	RXFP3 →	+0.068	+4.169	<.001	.008	3	2
BREAST	OOSP2 →	+0.017	+4.781	<.001	.003	3	2
SKIN	CMA1 →	+0.031	+2.681	<.001	<.001	3	2
LARGE_INTESTINE	SGMS2 →	+1.122	+3.949	<.001	<.001	3	2
LARGE_INTESTINE	FAM160A1 →	+0.679	+3.447	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 868 associations by consensus.

TAS2R9 by YLPM1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →