YKT6

Across TCGA patient cohorts, YKT6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,145 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible YKT6-associated genes across cancer lineages are KDELR2, RAC1, and PSMG3. Each is linked with YKT6 in more than 5 cancer types. Because this analysis shows association rather than direction, both YKT6-to-partner and partner-to-YKT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YKT6 versus KDELR2 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YKT6→partner) and Y-score (partner→YKT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KDELR2 →	+0.577	+0.268	.001	.001	3	6
LUAD	RAC1 →	+0.513	+0.307	<.001	<.001	3	5
LUAD	PSMG3 →	+0.562	+0.231	<.001	<.001	3	5
LUAD	PPIA →	+0.441	+0.209	<.001	<.001	3	5
LUAD	GARS1 →	+0.693	+0.336	<.001	<.001	3	5
OV	CALU →	+0.700	+0.311	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,145 associations by consensus.

YKT6 vs KDELR2 — OV

Explore this scatter interactively →