YKT6

Across TCGA cell cohorts, YKT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,607 significant associations in total. CNS shows the largest number of these associations.

The most reproducible YKT6-associated GO terms across cancer lineages are 2-oxoglutarate decarboxylation to succinyl-CoA, Endosomal transport, and Retrograde transport, endosome to Golgi. Each is linked with YKT6 in more than 15 cancer types. Because this analysis shows association rather than direction, both YKT6-to-partner and partner-to-YKT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 2-oxoglutarate decarboxylation to succinyl-CoA grouped by YKT6-low versus YKT6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YKT6→partner) and Y-score (partner→YKT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.148	+0.918	<.001	<.001	3	16
SKIN	Endosomal transport →	+0.064	+1.148	<.001	<.001	3	16
STOMACH	Retrograde transport, endosome to Golgi →	+0.091	+0.832	.001	.002	3	14
BONE	Vesicle-mediated transport to the plasma membrane →	+0.094	+0.845	<.001	<.001	3	14
BLOOD_Lymphoma	Spliceosomal tri-snRNP complex assembly →	+0.085	+1.015	<.001	<.001	3	13
BONE	Endocytic recycling →	+0.072	+0.710	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,607 associations by consensus.

2-oxoglutarate decarboxylation to succinyl-CoA by YKT6 expression — PANCREAS

Explore this box plot interactively →