YIPF6

Across TCGA patient cohorts, YIPF6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,741 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible YIPF6-associated genes across cancer lineages are PPP1R16B, OPTN, and FAM124A. Each is linked with YIPF6 in more than 3 cancer types. Because this analysis shows association rather than direction, both YIPF6-to-partner and partner-to-YIPF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YIPF6 versus PPP1R16B in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF6→partner) and Y-score (partner→YIPF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	-0.992	-0.224	<.001	<.001	3	4
UCEC	OPTN →	-0.546	-0.394	.004	.001	3	3
OV	FAM124A →	-0.665	-0.238	.005	<.001	3	3
LUAD	KCTD15 →	-0.623	-0.196	<.001	.007	3	3
HNSC	CMKLR1 →	-0.752	-0.331	.002	<.001	3	3
LSCC	PARD6G →	-0.540	-0.271	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,741 associations by consensus.

YIPF6 vs PPP1R16B — GBM

Explore this scatter interactively →