YIPF6

Across TCGA patient cohorts, YIPF6 mutation is significantly associated with the RNA expression of many other genes, with 1,521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF6-associated genes across cancer lineages are MIR8060, IGHV3OR16-8, and CCL5. Each is linked with YIPF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF6-to-partner and partner-to-YIPF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8060 grouped by YIPF6-low versus YIPF6-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF6→partner) and Y-score (partner→YIPF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR8060 →	+0.205	+7.471	<.001	.008	3	1
UCEC	IGHV3OR16-8 →	+0.514	+2.435	.005	<.001	3	1
UCEC	CCL5 →	+1.064	+1.758	<.001	.004	3	1
UCEC	ATP1B3P1 →	+0.276	+2.337	<.001	.004	3	1
UCEC	LINC01607 →	-0.667	-2.481	<.001	.001	3	1
UCEC	LINC02084 →	+0.371	+1.939	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,521 associations by consensus.

MIR8060 by YIPF6 expression — BRCA

Explore this box plot interactively →