YIPF5

Across TCGA patient cohorts, YIPF5 mutation is significantly associated with the RNA expression of many other genes, with 968 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF5-associated genes across cancer lineages are RNA5SP412, MIR6803, and SPCS2P2. Each is linked with YIPF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF5-to-partner and partner-to-YIPF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by YIPF5-low versus YIPF5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF5→partner) and Y-score (partner→YIPF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.599	+2.774	<.001	<.001	3	2
UCEC	MIR6803 →	+0.183	+4.777	<.001	.002	3	2
UCEC	SPCS2P2 →	+0.065	+2.476	<.001	.009	3	1
UCEC	IRF2-DT →	-0.523	-3.785	<.001	<.001	3	1
UCEC	SNX29P2 →	+0.068	+2.181	.005	.004	3	1
UCEC	RBAK-RBAKDN →	+0.124	+2.727	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 968 associations by consensus.

RNA5SP412 by YIPF5 expression — UCEC

Explore this box plot interactively →