YIPF1

Across TCGA patient cohorts, YIPF1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF1-associated genes across cancer lineages are Erythrocytes, lymphatic Endothelial cells, and Mesangial cells. Each is linked with YIPF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF1-to-partner and partner-to-YIPF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by YIPF1-low versus YIPF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF1→partner) and Y-score (partner→YIPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.038	+3.071	.002	.017	3	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.138	.028	.019	3	1
UCEC	Mesangial cells →	-0.045	-2.983	.020	.036	3	1
UCEC	Plasma cells →	-0.022	-3.416	.039	.005	3	1
UCEC	Class-switched memory B-cells →	-0.058	-2.892	.042	.025	2	1
UCEC	Basophils →	+0.212	+3.169	.012	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Erythrocytes by YIPF1 expression — UCEC

Explore this box plot interactively →