YIPF1

Across TCGA cell cohorts, YIPF1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YIPF1-associated genes across cancer lineages are OR12D3, GPR42, and FCN2. Each is linked with YIPF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF1-to-partner and partner-to-YIPF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D3 grouped by YIPF1-low versus YIPF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF1→partner) and Y-score (partner→YIPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR12D3 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	GPR42 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	FCN2 →	+0.039	+4.415	<.001	.007	3	1
LARGE_INTESTINE	GK2 →	+0.010	+5.022	<.001	.002	3	1
LARGE_INTESTINE	MAGEB3 →	+0.060	+4.467	<.001	.004	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR12D3 by YIPF1 expression — LARGE_INTESTINE

Explore this box plot interactively →