YIF1B

Across TCGA patient cohorts, YIF1B mutation is significantly associated with the RNA expression of many other genes, with 210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIF1B-associated genes across cancer lineages are CKS1BP5, RNU6-1227P, and VN1R18P. Each is linked with YIF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both YIF1B-to-partner and partner-to-YIF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CKS1BP5 grouped by YIF1B-low versus YIF1B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIF1B→partner) and Y-score (partner→YIF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CKS1BP5 →	+0.234	+5.332	<.001	.002	3	2
BLCA	RNU6-1227P →	+0.364	+5.411	<.001	.005	3	2
BRCA	VN1R18P →	+0.059	+6.016	<.001	.002	3	1
BRCA	MIR3169 →	+0.168	+7.471	<.001	.008	3	1
SKCM	RNU7-133P →	+0.582	+5.436	<.001	.005	3	1
COAD	MDH1P2 →	+0.136	+3.792	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 210 associations by consensus.

CKS1BP5 by YIF1B expression — COAD

Explore this box plot interactively →