YEATS4

Across TCGA cell cohorts, YEATS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,128 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YEATS4-associated GO terms across cancer lineages are Antigen processing and presentation of peptide antigen via MHC class I, Antigen processing and presentation of endogenous antigen, and Positive regulation of mitochondrial ATP synthesis coupled electron transport. Each is linked with YEATS4 in more than 13 cancer types. Because this analysis shows association rather than direction, both YEATS4-to-partner and partner-to-YEATS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of peptide antigen via MHC class I grouped by YEATS4-low versus YEATS4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YEATS4→partner) and Y-score (partner→YEATS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Antigen processing and presentation of peptide antigen via MHC class I →	-0.178	-0.847	.003	.004	3	14
BREAST	Antigen processing and presentation of endogenous antigen →	-0.273	-1.066	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.190	+0.905	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of centriole replication →	+0.100	+1.196	<.001	<.001	3	13
BLOOD_Lymphoma	DAMP biosynthetic process →	+0.120	+1.222	<.001	<.001	3	12
BONE	Recombinational repair →	+0.083	+0.758	.005	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,128 associations by consensus.

Antigen processing and presentation of peptide antigen via MHC class I by YEATS4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →