YDJC

Across TCGA patient cohorts, YDJC protein abundance is significantly associated with the RNA expression of many other genes, with 4,222 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible YDJC-associated genes across cancer lineages are DNMT3B, UHRF1BP1L, and PEX7. Each is linked with YDJC in more than 2 cancer types. Because this analysis shows association rather than direction, both YDJC-to-partner and partner-to-YDJC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YDJC versus DNMT3B in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YDJC→partner) and Y-score (partner→YDJC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNMT3B →	-0.917	-0.622	<.001	.003	3	3
BRCA	UHRF1BP1L →	+0.494	+0.279	.001	.003	3	2
BRCA	PEX7 →	+0.681	+0.377	<.001	<.001	3	2
BRCA	PTK7 →	-1.020	-0.419	.001	<.001	3	2
BRCA	SCPEP1 →	-0.854	-0.343	<.001	.002	3	2
BRCA	OR2B6 →	-0.799	-0.291	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,222 associations by consensus.

YDJC vs DNMT3B — OV

Explore this scatter interactively →