YBX1

Across TCGA patient cohorts, YBX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,580 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible YBX1-associated proteins across cancer lineages are PURA, NRDC, and CDC20_T70. Each is linked with YBX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both YBX1-to-partner and partner-to-YBX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YBX1 versus PURA in OV, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX1→partner) and Y-score (partner→YBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PURA →	-0.599	-0.575	<.001	.001	3	9
BRCA	NRDC →	+0.332	+0.646	<.001	<.001	3	9
BRCA	CDC20_T70 →	+1.277	+1.043	<.001	<.001	3	8
GBM	SMC2 →	+0.704	+0.538	<.001	<.001	3	8
GBM	SMC4 →	+0.651	+0.494	<.001	<.001	3	8
GBM	NCAPD2 →	+0.670	+0.520	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,580 associations by consensus.

YBX1 vs PURA — OV

Explore this scatter interactively →