YARS2

Across TCGA patient cohorts, YARS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,309 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YARS2-associated proteins across cancer lineages are DNM1L, WDR12, and UTP4. Each is linked with YARS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both YARS2-to-partner and partner-to-YARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YARS2 versus DNM1L in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YARS2→partner) and Y-score (partner→YARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNM1L →	+0.420	+0.606	<.001	.001	3	7
GBM	WDR12 →	+0.435	+0.238	<.001	<.001	3	6
BRCA	UTP4 →	+0.485	+0.599	<.001	<.001	3	6
BRCA	WDR36 →	+0.404	+0.549	<.001	<.001	3	5
BRCA	ZNF638 →	+0.224	+0.460	<.001	.001	3	5
LSCC	RPUSD2 →	+0.313	+0.401	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,309 associations by consensus.

YARS2 vs DNM1L — BRCA

Explore this scatter interactively →