YAE1

Across TCGA patient cohorts, YAE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,796 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YAE1-associated proteins across cancer lineages are PURB, NUDCD3, and UNC13D. Each is linked with YAE1 in more than 7 cancer types. Because this analysis shows association rather than direction, both YAE1-to-partner and partner-to-YAE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YAE1 versus PURB in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YAE1→partner) and Y-score (partner→YAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PURB →	+0.561	+0.488	<.001	<.001	3	8
LUAD	NUDCD3 →	+0.269	+0.383	<.001	<.001	3	8
GBM	UNC13D →	-0.319	-0.305	.001	<.001	3	6
LUAD	C7orf50 →	+0.428	+0.502	<.001	<.001	3	6
BRCA	CRLF3 →	-0.361	-0.379	.001	<.001	3	6
LSCC	FOXK1 →	+0.284	+0.401	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,796 associations by consensus.

YAE1 vs PURB — OV

Explore this scatter interactively →