YAE1

Across TCGA cell cohorts, YAE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,031 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible YAE1-associated GO terms across cancer lineages are Aerobic electron transport chain, Positive regulation of chromosome organization, and rRNA 2'-O-methylation. Each is linked with YAE1 in more than 7 cancer types. Because this analysis shows association rather than direction, both YAE1-to-partner and partner-to-YAE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by YAE1-low versus YAE1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YAE1→partner) and Y-score (partner→YAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Aerobic electron transport chain →	+0.064	+0.660	.001	.002	3	8
SKIN	Positive regulation of chromosome organization →	+0.064	+0.819	<.001	<.001	3	8
SKIN	rRNA 2'-O-methylation →	+0.088	+0.754	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of nuclear division →	+0.089	+0.644	.006	.001	3	8
BREAST	Cellular response to corticosteroid stimulus →	-0.106	-0.538	.002	.007	3	8
SOFT_TISSUE	Negative regulation of mitotic nuclear division →	+0.091	+0.651	.005	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,031 associations by consensus.

Aerobic electron transport chain by YAE1 expression — SKIN

Explore this box plot interactively →