XYLB

Across TCGA patient cohorts, XYLB RNA expression is significantly associated with the protein abundance of many other proteins, with 15,568 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XYLB-associated proteins across cancer lineages are XYLB_S354, HNRNPU, and WDR5. Each is linked with XYLB in more than 6 cancer types. Because this analysis shows association rather than direction, both XYLB-to-partner and partner-to-XYLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XYLB versus XYLB_S354 in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLB→partner) and Y-score (partner→XYLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XYLB_S354 →	+0.972	+0.569	<.001	<.001	3	7
HNSC	HNRNPU →	+0.222	+0.619	.001	.003	3	6
GBM	WDR5 →	+0.331	+0.459	<.001	.002	3	5
OV	NELFE →	+0.679	+0.595	<.001	.002	3	5
GBM	TOP2B →	+0.356	+0.441	.004	.003	3	5
OV	PUF60 →	+0.393	+0.428	.004	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,568 associations by consensus.

XYLB vs XYLB_S354 — LSCC

Explore this scatter interactively →