XYLB

Across TCGA patient cohorts, XYLB protein abundance is significantly associated with the RNA expression of many other genes, with 7,623 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible XYLB-associated genes across cancer lineages are VGLL4, ZNF619, and DHRS4-AS1. Each is linked with XYLB in more than 3 cancer types. Because this analysis shows association rather than direction, both XYLB-to-partner and partner-to-XYLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XYLB versus VGLL4 in COAD, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLB→partner) and Y-score (partner→XYLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VGLL4 →	+0.448	+0.311	<.001	.002	3	4
OV	ZNF619 →	+0.521	+0.348	<.001	<.001	3	4
CCRCC	DHRS4-AS1 →	+0.552	+0.346	<.001	<.001	3	4
BRCA	EPSTI1 →	-0.726	-0.218	<.001	.006	3	3
CCRCC	IL17RD →	+0.821	+0.287	<.001	<.001	3	3
BRCA	DOK2 →	-0.868	-0.300	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,623 associations by consensus.

XYLB vs VGLL4 — COAD

Explore this scatter interactively →