XYLB

Across TCGA cell cohorts, XYLB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,730 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible XYLB-associated GO terms across cancer lineages are IMP biosynthetic process, Regulation of centriole-centriole cohesion, and DNA replication. Each is linked with XYLB in more than 14 cancer types. Because this analysis shows association rather than direction, both XYLB-to-partner and partner-to-XYLB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by XYLB-low versus XYLB-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLB→partner) and Y-score (partner→XYLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IMP biosynthetic process →	+0.152	+0.971	<.001	<.001	3	15
BLOOD_Myeloma	Regulation of centriole-centriole cohesion →	+0.169	+0.903	<.001	<.001	3	13
SOFT_TISSUE	DNA replication →	+0.109	+0.939	<.001	<.001	3	12
BLOOD_Myeloma	DNA-templated DNA replication →	+0.120	+0.839	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair via homologous recombination →	+0.088	+0.912	<.001	<.001	3	12
BONE	Pentose catabolic process →	-0.211	-1.240	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,730 associations by consensus.

IMP biosynthetic process by XYLB expression — SOFT_TISSUE

Explore this box plot interactively →