XYLB

Across TCGA cell cohorts, XYLB protein abundance is significantly associated with the RNA expression of many other genes, with 2,649 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XYLB-associated genes across cancer lineages are TCAF1, CDHR2, and SLC30A5. Each is linked with XYLB in more than 4 cancer types. Because this analysis shows association rather than direction, both XYLB-to-partner and partner-to-XYLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XYLB versus TCAF1 in BLOOD_Leukemia, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLB→partner) and Y-score (partner→XYLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCAF1 →	+1.104	+0.444	.001	<.001	3	5
LIVER	CDHR2 →	+2.004	+0.512	.005	.009	3	4
URINARY_TRACT	SLC30A5 →	+0.722	+0.668	<.001	<.001	3	4
URINARY_TRACT	ASTE1 →	+0.492	+0.629	.009	.002	3	4
LUNG_SCLC	KLF13 →	+0.976	+0.633	<.001	<.001	3	4
BLOOD_Lymphoma	FAF2 →	+0.916	+0.658	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,649 associations by consensus.

XYLB vs TCAF1 — BLOOD_Leukemia

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