XXYLT1-AS1

Across TCGA pan-cancer cohorts, XXYLT1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated XXYLT1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher XXYLT1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated XXYLT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and HNSC show a favorable association.

MESO, PAAD, and HNSC are the cancer types where XXYLT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.471	0.270	.002	118	view →
PAAD	OS	Quartile	All	0.218	0.503	<.001	68	view →
HNSC	DFS	Quartile	IV	0.748	0.543	.004	57	view →
LUSC	OS	Tertile	All	0.749	0.599	<.001	40	view →
BLCA	DFS	Median	IV	0.270	0.437	.009	28	view →
THYM	OS	Quartile	All	0.827	1.000	.002	21	view →
CESC	DFS	Quartile	All	0.896	0.759	.003	20	view →
COAD	DFS	Quartile	II,III,IV	0.527	0.726	.007	19	view →
BRCA	OS	Quartile	IV	1.000	0.375	.010	15	view →
KIRP	DFS	Median	All	0.962	0.867	.004	12	view →
SARC	DFS	Tertile	All	0.673	0.482	.017	12	view →
LIHC	DFS	Tertile	All	0.273	0.550	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

XXYLT1-AS1–MESO (OS)

Open the MESO breakdown →