XRCC6P5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, XRCC6P5 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XRCC6P5-associated genes across cancer lineages are eIF4E, A-Raf_pS299, and ERK2. Each is linked with XRCC6P5 in more than 1 cancer types. Because this analysis shows association rather than direction, both XRCC6P5-to-partner and partner-to-XRCC6P5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC6P5→partner) and Y-score (partner→XRCC6P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeIF4E →+0.204+3.472.007.00232
UCECA-Raf_pS299 →-0.169-2.807<.001.00232
UCECERK2 →+0.184+2.115.007.01732
UCECJNK2 →+0.297+2.321<.001.00132
UCECMEK1 →+0.447+2.807<.001<.00132
UCECp38-MAPK_pT180_Y182 →-0.405-2.115.012.01732
Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration