XPR1

Across TCGA patient cohorts, XPR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,863 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XPR1-associated proteins across cancer lineages are KIDINS220, KIDINS220_S918, and PMVK. Each is linked with XPR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both XPR1-to-partner and partner-to-XPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPR1 versus KIDINS220 in UCEC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XPR1→partner) and Y-score (partner→XPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIDINS220 →	+0.565	+0.751	<.001	<.001	3	7
UCEC	KIDINS220_S918 →	+0.794	+0.549	<.001	<.001	2	6
UCEC	PMVK →	+0.533	+0.654	<.001	<.001	3	5
GBM	DHX9 →	+0.185	+0.455	<.001	<.001	3	5
LSCC	IPO9 →	+0.358	+0.728	<.001	<.001	3	5
UCEC	UCHL5 →	+0.210	+0.433	.004	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,863 associations by consensus.

XPR1 vs KIDINS220 — UCEC

Explore this scatter interactively →