Across TCGA cell cohorts, XPOT RNA expression is significantly associated with the RNA expression of many other genes, with 8,258 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible XPOT-associated genes across cancer lineages are YARS1, IARS1, and CCNT1. Each is linked with XPOT in more than 17 cancer types. Because this analysis shows association rather than direction, both XPOT-to-partner and partner-to-XPOT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPOT→partner) and Y-score (partner→XPOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	YARS1 →	+1.163	+1.112	<.001	<.001	3	18
OESOPHAGUS	IARS1 →	+1.492	+1.710	<.001	<.001	2	17
STOMACH	CCNT1 →	+1.056	+1.272	<.001	<.001	3	16
OESOPHAGUS	MARS1 →	+1.453	+1.428	.002	.001	2	17
SOFT_TISSUE	ZNF770 →	+1.260	+1.016	<.001	<.001	3	15
OESOPHAGUS	CEBPG →	+1.111	+0.988	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,258 associations by consensus.

Exploration

XPOT survival (RNA) · tumor vs normal (RNA) · all XPOT data types