XPO4

Across TCGA patient cohorts, XPO4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,368 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XPO4-associated proteins across cancer lineages are DIS3, HMGB1, and RBM26. Each is linked with XPO4 in more than 5 cancer types. Because this analysis shows association rather than direction, both XPO4-to-partner and partner-to-XPO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPO4 versus DIS3 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XPO4→partner) and Y-score (partner→XPO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DIS3 →	+0.255	+0.382	<.001	<.001	3	6
COAD	HMGB1 →	+0.367	+0.375	<.001	.001	3	6
LSCC	RBM26 →	+0.280	+0.496	<.001	<.001	3	6
GBM	ZMYM2 →	+0.329	+0.331	<.001	<.001	3	5
GBM	ZMYM2_S624 →	+0.762	+0.619	<.001	<.001	3	5
GBM	ZC3H13 →	+0.240	+0.373	.009	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,368 associations by consensus.

XPO4 vs DIS3 — LUAD

Explore this scatter interactively →