XPO4

Across TCGA patient cohorts, XPO4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,861 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible XPO4-associated genes across cancer lineages are MIPEP, MICU2, and SUPT20H. Each is linked with XPO4 in more than 7 cancer types. Because this analysis shows association rather than direction, both XPO4-to-partner and partner-to-XPO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPO4 versus MIPEP in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPO4→partner) and Y-score (partner→XPO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIPEP →	+0.621	+0.240	.002	<.001	3	8
OV	MICU2 →	+0.435	+0.182	<.001	<.001	3	6
HNSC	SUPT20H →	+0.525	+0.194	.009	.001	2	6
LSCC	MTRF1 →	+0.466	+0.177	<.001	.001	3	5
HNSC	ALG5 →	+0.536	+0.180	<.001	<.001	3	5
HNSC	EXOSC8 →	+0.623	+0.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,861 associations by consensus.

XPO4 vs MIPEP — HNSC

Explore this scatter interactively →