XPO4

Across TCGA cell cohorts, XPO4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,357 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XPO4-associated genes across cancer lineages are FANCA, PPT2, and WNT10B. Each is linked with XPO4 in more than 5 cancer types. Because this analysis shows association rather than direction, both XPO4-to-partner and partner-to-XPO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPO4 versus FANCA in BREAST, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPO4→partner) and Y-score (partner→XPO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	FANCA →	+1.007	+1.029	<.001	<.001	3	5
LIVER	PPT2 →	+0.964	+0.898	.005	.006	1	6
OESOPHAGUS	WNT10B →	+2.036	+1.739	.008	.001	3	4
STOMACH	ZNF276 →	+1.259	+1.201	.005	.002	3	4
BREAST	MMS22L →	+0.881	+0.742	.001	.003	2	5
KIDNEY	MGAT2 →	+0.823	+1.391	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,357 associations by consensus.

XPO4 vs FANCA — BREAST

Explore this scatter interactively →