Across TCGA patient cohorts, XPNPEP3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XPNPEP3-associated genes across cancer lineages are PCNA, mTOR_pS2448, and 4E-BP1. Each is linked with XPNPEP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both XPNPEP3-to-partner and partner-to-XPNPEP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPNPEP3→partner) and Y-score (partner→XPNPEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.182	+1.678	.028	.023	3	3
UCEC	mTOR_pS2448 →	-0.137	-1.986	.016	.029	3	2
UCEC	4E-BP1 →	+0.267	+3.199	.010	.009	3	2
UCEC	Di-Ras3 →	-0.138	-3.308	.015	.009	3	2
UCEC	14-3-3_beta →	-0.098	-2.295	.011	.033	3	1
UCEC	EGFR_pY1068 →	-0.221	-2.000	.021	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

XPNPEP3 survival (RNA) · tumor vs normal (RNA) · all XPNPEP3 data types