XKRX

Across TCGA patient cohorts, XKRX RNA expression is significantly associated with the RNA expression of many other genes, with 16,724 significant associations in total. UVM shows the largest number of these associations.

The most reproducible XKRX-associated genes across cancer lineages are HNRNPA1P27, NSA2P3, and CSGALNACT2P1. Each is linked with XKRX in more than 29 cancer types. Because this analysis shows association rather than direction, both XKRX-to-partner and partner-to-XKRX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XKRX versus HNRNPA1P27 in LUAD, with a Pearson correlation of 0.90.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XKRX→partner) and Y-score (partner→XKRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HNRNPA1P27 →	+2.420	+2.467	<.001	<.001	3	30
LUAD	NSA2P3 →	+2.124	+2.425	<.001	<.001	3	29
LAML	CSGALNACT2P1 →	+0.549	+0.313	<.001	<.001	3	26
ACC	RBM41 →	+0.758	+0.382	<.001	.008	2	27
ACC	IFNLR1 →	+1.137	+0.574	<.001	<.001	3	25
SCLC	EXPH5 →	+0.889	+0.914	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,724 associations by consensus.

XKRX vs HNRNPA1P27 — LUAD

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