Q-omics provides the consensus-scored NSA2P3 profile across patient tissues and cancer cell-line models. NSA2P3 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, NSA2P3 is differentially expressed in 10, with the highest sampling consensus in THCA. Additionally, NSA2P3 RNA expression shows 13,070 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, THCA, and THYM as cancer lineages where NSA2P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NSA2P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NSA2P3 survival associations across molecular data types. NSA2P3 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NSA2P3 RNA expression–survival associations across cancer types. High NSA2P3 expression shows unfavorable associations in KIRP, but favorable associations in KIRC, UCEC, LUAD, READ and BRCA. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for NSA2P3 RNA expression.
This table summarizes NSA2P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for NSA2P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NSA2P3 shows lower tumor expression in HNSC and higher tumor expression in THCA, LUAD, KIRC, COAD and LIHC. The THCA box plot shows higher NSA2P3 RNA expression in tumor versus normal tissue (log2 FC = +1.403, t-test p < 0.001).
This table shows molecular features associated with NSA2P3 in patient tissues and cancer cell lines. In patient samples, NSA2P3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
