XIRP2-AS1

Across TCGA pan-cancer cohorts, XIRP2-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of XIRP2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where XIRP2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types XIRP2-AS1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC and KIRP are the cancer types where XIRP2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in XIRP2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.022	<.001	8	view →
KIRP	Male	III,IV	+0.043	.030	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

XIRP2-AS1–KIRC

Open the KIRC breakdown →