XIRP1

Across TCGA patient cohorts, XIRP1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,682 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible XIRP1-associated genes across cancer lineages are TNFSF4, GRIP2, and CYTH4. Each is linked with XIRP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both XIRP1-to-partner and partner-to-XIRP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XIRP1 versus TNFSF4 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XIRP1→partner) and Y-score (partner→XIRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNFSF4 →	+0.924	+0.759	.001	.001	3	5
CCRCC	GRIP2 →	+0.634	+0.835	.004	.004	3	5
HNSC	CYTH4 →	+0.651	+0.906	.007	<.001	3	4
UCEC	IL21R →	+0.967	+0.757	.006	.004	2	5
BRCA	GBP1 →	+1.209	+0.846	<.001	<.001	3	4
HNSC	FAM78A →	+1.003	+1.504	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,682 associations by consensus.

XIRP1 vs TNFSF4 — UCEC

Explore this scatter interactively →