XIRP1

Across TCGA pan-cancer cohorts, XIRP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of XIRP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where XIRP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types XIRP1 is over-expressed in tumor.

LUAD, STAD, and LIHC are the cancer types where XIRP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in XIRP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.682	<.001	9	view →
STAD	All	II,III,IV	+0.477	<.001	8	view →
LIHC	All	II,III,IV	+0.077	.006	6	view →
COAD	Female	All	+0.222	<.001	5	view →
BRCA	Female	All	+0.578	<.001	4	view →
CHOL	All	II,III,IV	+0.145	.045	2	view →
KIRC	All	All	+0.096	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

XIRP1–LUAD

Open the LUAD breakdown →